New from Adisseo

Smartamine® MAX

The new standard in rumen-protected methionine

When results matter, MAX matters most.

80%DL-Methionine
×
80%Bioavailability
=
64%Metabolizable Methionine
(640 g/kg)
Smartamine MAX capsule releasing protected methionine, supporting health, production, reproduction, longevity and sustainability
Health
Production
Reproduction
Longevity
Sustainability
Built on the trusted Smartamine legacy

The best legacies don’t end, they evolve.

For more than 30 years, Smartamine® M has set the benchmark for reliable methionine delivery and consistent results, supported by extensive scientific research and used in the diets of 2.5 million cows worldwide. Smartamine® MAX builds on that legacy.

Smartamine MAX combines two patented technologies: a unique methionine core formulation and a pH-sensitive, biopolymer-based coating that protects methionine through the rumen and enables targeted release for absorption.

5years of focused development
70prototypes evaluated47 lab-scale · 21 industrial-scale
15in vivo dose-response studies
2scientific publications

Smartamine MAX at a glance

Metabolizable methionine64% (640 g/kg)
DL-Methionine content≥ 80%
Bioavailability80%
Protection rate> 94%
CoatingpH-sensitive, biopolymer-based
TechnologyPatented core + coating
ValidationUNH in vivo trials
Engineered, tested, and refined

Five years to set a higher standard

In vivo evaluations at the University of New Hampshire (UNH) guided the development and refinement of Smartamine MAX to deliver 64% metabolizable methionine (mMet), above the 60% industry benchmark.

Graph 1 · mMet of successive prototypes evaluated during development

Bar chart: mMet of successive prototypes rose from about 49% to the final Smartamine MAX formulation at 64%, compared with the 60% Smartamine M industry benchmark.

Swipe to see the full chart →

Formulate with confidence

Deliver what you expect.

When product specifications overestimate mMet delivery, the cow receives less than you formulate for, creating a gap that can limit expected performance (money wasted).

Graph 2 · Actual mMet delivered when formulating for 10 g mMet/cow/day

Targeted delivery (manufacturer specifications) vs. actual delivery (based on UNH in vivo bioavailability testing).

Target: 10 g mMet

Smartamine® MAX
10.0 g
Smartamine® M
10.0 g
Product B
−4.7 g
5.3 g
Product C
−6.8 g
3.2 g
Product D
−4.7 g
5.3 g
Product E
−6.9 g
3.1 g
Product F
−7.9 g
2.1 g
Product G
−8.7 g
1.3 g
Actual mMet delivered Targeted but not delivered
More methionine, more performance, more value

When results matter, MAX matters most

Unlock the full potential of dairy cow health, production, reproduction and longevity.

Health

  • Better liver health
  • Less inflammation
  • Increased antioxidant status
  • Fewer post-partum diseases

Production

  • +0.1 lb milk protein
  • +0.12 lb milk fat
  • +2.1 lb ECM

Reproduction

  • Reduced embryonic losses
  • Increased pregnancy rate
  • Positive fetal programming

Longevity

  • Decreased involuntary culling
  • Better repro and performance

Sustainability

  • Improved nitrogen efficiency
  • Reduced carbon footprint
Quality you can trust

Rigorous quality control in every industrial batch

Smartamine® MAX undergoes a rigorous three-step quality control process to ensure consistent delivery of metabolizable methionine. Our proprietary laboratory methods are calibrated against bioavailability measurements in lactating cow trials at UNH and verify each critical specification.

Every batch must pass all three steps before it is released for sale.

Smartamine MAX bag
STEP1
DL-Met Content

≥ 80%DL-Methionine

Each batch is verified to contain a minimum of 80% DL-Methionine.

How it’s tested
  • Grinding of Smartamine MAX
  • Extraction of methionine
  • Separation and UV quantification at 205 nm
STEP2
Rumen Protection

> 94%Protection rate

Verified using validated proprietary lab methods. Only batches meeting the protection spec are released, ensuring consistent rumen bypass.

How it’s tested
  • Beadlets placed in a buffer solution (pH 6.0, 40°C for 4 h)
  • Analysis of the supernatant solution
  • Separation and UV quantification at 205 nm
STEP3
Biopolymer Content

OptimalBiopolymer content

Verified as a proxy for abomasal release, so methionine is released where the cow can absorb it.

How it’s tested
  • Chitosan content in the coating is tightly controlled to defined specifications for every batch.
  • Coating rate is controlled through in-process analytical checks for both protection and release performance.

See how Smartamine MAX fits your ration. Our team can walk you through the data and specifications.

Contact Our Team
Manufacturing excellence

A dedicated production line

Smartamine MAX is produced exclusively at Adisseo’s Commentry facility in France.

A dedicated coating-solution production line was built alongside the existing Smartamine® M line, so every batch of Smartamine MAX is made to its own specification, with the same manufacturing expertise behind it.

Adisseo Commentry production facility
Talk to our team

Ready to raise your methionine standard?

Our team can help you formulate with Smartamine® MAX and answer questions about switching, specifications and pricing.

Put Smartamine MAX to work in your herd

Calculate your ROI with MilkSmart 3.0

A free tool that estimates the production and economic value of optimized methionine nutrition across your cows’ lifetime performance.

  1. Input details from your herd.
  2. Adjust for Smartamine MAX inclusion.
  3. Instantly see the IOFC from amino acid balancing.

Questions about your results? Contact our team.

MilkSmart by Adisseo IOFC calculator on a tablet