Ketosis is a common disease. The estimated cost of subclinical ketosis is $67 USD per case per year. With clinical ketosis, the cost climbs to an estimated $232 USD per case per year. During episodes of negative energy balance, such as transition and early lactation, fortifying the metabolizable methionine content of diets with rumen-protected methionine products, like Smartamine® M or MetaSmart®, helps support the onset of lactation by mitigating common metabolic health challenges such as ketosis
Feeding rumen-protected methionine sources, pre- and postpartum, has shown to positively impact dry matter intake, milk and components, and metabolic health with a lower incidence of ketosis. This sets cows up for healthy and profitable lactations.

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https://www.adisseo.com/en/optimize-cow-performance-and-health-with-supplemental-methionine-adisseo/