Get The Most Out of Your Organic Selenium Supplementation With Selisseo®
WHY SELISSEO® ?

Selisseo contains 100% hydroxy-selenomethionine, a pure and highly available form of organic selenium.
Selenium is an essential trace mineral for animal nutrition. It plays a key role in antioxidant defense, immunity, reproduction, and inflammatory modulation processes. While inorganic Se sources, such as sodium selenite (SS), are commonly used as feed supplements, recent research confirmed that organic Se, specifically selenomethionine (SeMet) or hydroxy-selenomethionine (OH-SeMet), is much more easily integrated into the body.
Selisseo® is FDA-approved for use in poultry, swine, and cattle in the US and approved for use in all species in Canada.

CONSISTENTLY PROVIDES
100% PURE OH-SeMet
On average, Selenium Yeast (SY) products contain 60% SeMet and the amount of SeMet varies from batch to batch, while Selisseo® consistently provides 100% selenium as OH-SeMet, batch after batch.
Selisseo’s consistent particle size without fines makes for safe and easy mixing in the feed with low dust levels.
HER BENEFITS
Selisseo® helps maintain higher milk yield and milk quality under challenging conditions (such as parturition and heat stress) while enhancing the cow’s antioxidant functions.
HER BENEFITS
- Improved dairy cow Se status: Increased Se storage in both the plasma (+125% vs SS (1), +7% vs SY (2)) and milk (+22.8% vs SS(1) + 18% vs SY (2))
- Better antioxidant status: higher activity of glutathione peroxidase (+46%) and Total antioxidant capacity (+19.6% vs SS)(1)
- Lower somatic cell count:
- 0.1 ppm Selisseo delivered similar results to Selenium Yeast 0.3 ppm
- 0.3 ppm Selisseo (recommended usage) provided a 64% SCC reduction compared to Selenium Yeast (2)
- Lower drop in milk yield: When under heat stress: +9.3% vs SS (3)
- Positive modulation of several oxidative stress biomarkers under heat stress conditions:
- Improved total antioxidant capacity (+20% vs SS) (3)
- Lower plasma H2 O2 (-18.5% vs SS) (3)
- Lower plasma nitric oxide (-22.9% vs SS) (3)
BENEFITS FOR CALVES
BENEFITS FOR CALVES
Selisseo® allows selenium to be transferred from the dam to the calf, promoting calf health.
- Higher Se content in heifers plasma:
- +13% at 2 weeks pre-calving & +16% at calving vs SS (4)
- Higher Se content in colostrum:
- +20% vs SS (4)
- Increased Se status of newborn calves:
- +14% vs SS (4)
(1) Sun et al., 2017, Journal of Dairy Science. 100(12), 9602-9610
(2) Hachemi et al, 2023. Journal of Dairy Science. 106:1 -12
(3) Sun et al., 2019, Journal of Dairy Science. 102(1), 311-319
(4) Juniper et al., 2019, Journal of Dairy Science, 1102(8 ), 7000-7010
More data is available upon request.
Even in challenging conditions, performance will be supported.
Animals experience various stresses throughout their life. To restore antioxidant balance and performance of the animal, Adisseo offers Selisseo. Watch this video to learn more about Selenium and Selisseo.
More Scientific Research
Inorganic and Organic Selenium Speciation of Seleno‑Yeasts
Used as Feed Additives
New Insights from Elemental Selenium
Determination.
Seleno-Yeasts (SY) used as feed additives are known to contain different Selenium (Se) species. Seleno-Yeasts has been shown, on previous analytical methods, to contain selenomethionine (SeMet), selenocysteine (SeCys), selenate (SeIV), and selenite (SeVI), and various other organic and inorganic Se forms identified but rarely quantified…
Understanding Selenium
with Dr. Nancy Whitehouse
Understanding Selenium with Dr. Nancy Whitehouse
On The Dairy Podcast:
Dr. Nancy Whitehouse: Benefits of Organic Selenium
Meet the guest: Dr. Nancy Whitehouse, assistant research professor at The University of New Hampshire
Resources
Check out our resources to learn more about how these products can help you!
Research has shown that Selenium is effective in reducing some of the negative effects of heat stress (HS) in dairy cows...
Introducing Selisseo, 100% hydroxy-selenomethionine (OH-SeMet), a pure and highly-available form of organic selenium.
In this 4 part video series on Selisseo®, we enlist the help of key Adisseo employees to explain the creation and uses of Adisseo’s pure organic selenium, a nutritional feed supplement for livestock.
Effective selenium supplementation provides optimal antioxidant protection, and ensures the performance of dairy cows and calves, particularly during times of stress, to maintain a higher level of both milk yield and quality.
Research has shown that Selenium is effective in reducing some of the negative effects of heat stress (HS) in dairy cows...
Introducing Selisseo, 100% hydroxy-selenomethionine (OH-SeMet), a pure and highly-available form of organic selenium.
In this 4 part video series on Selisseo®, we enlist the help of key Adisseo employees to explain the creation and uses of Adisseo’s pure organic selenium, a nutritional feed supplement for livestock.
Effective selenium supplementation provides optimal antioxidant protection, and ensures the performance of dairy cows and calves, particularly during times of stress, to maintain a higher level of both milk yield and quality.